Northeast Regional Life Sciences Core Directors Meeting
October 24-26, 2012
Mountain View Grand Resort
Whitefield, NH
Satellite Meetings and Tours
Satellite events held before and during the NERLSCD 2011 meeting included:
(1) The Northeast Symposium on Proteomics and Protein Chemistry
(2) Cornell Institute for Genomic Diversity: Educational Workshop on Genotyping-by-Sequencing
(3) New York Core Administration Network (NY-CAN) Meeting
(4) Tours of Cores
(5) A Taste of Ithaca: Dinner Groups
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The Northeast Symposium on Proteomics and Protein Chemistry:
Improved Strategies for the Analysis of Proteins, Protein Complexes and Proteomics
Organizers, Michelle Cilia and Ted Thannhauser, Robert W. Holley Center for Agriculture and Health, USDA-ARS
9:00 am - 4:00 pm
Wednesday, November 9th, 2011
1st Floor Auditorium
Boyce Thompson Institute for Plant Research
Cornell University
533 Tower Road
Ithaca, NY 14853-1801
The first annual Northeast Symposium on Proteomics and Protein Chemistry (NESPPC) was free and open to the public. The scheduling of this event was set to coordinate with the NERLSCD 2011 meeting. All NERLSCD attendees were encouraged to attend. The symposium speakers included Jim Bruce,University of Washington, Ileana Cristea, Princeton University, Jay Fox, University of Virginia, Arthur Moseley, Duke University School of Medicine, Darryl Pappin, Cold Spring Harbor Laboratory, Jocelyn Rose, Cornell University, Cristian Ruse, Cold Spring Harbor Laboratory, Marcus Smolka, Cornell University, and Klaas Van Wijk, Cornell University. Pre-registration was requested. For additional information about this symposium, please contact Michelle Cilia or Ted Thannhauser.
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Cornell Institute for Genomic Diversity:
Educational Workshop on Genotyping-by-Sequencing (GBS)
Organizer: Robert Elshire, Institute for Genomic Diversity, Cornell University
12:00 - 3:00 pm
Wednesday, November 9th, 2011
ILR Conference Center - Room 229
Cornell University
Ithaca, NY 14853
Producing genotypic data has long been a costly and challenging component of genetic studies. Current methods generally require a marker development phase followed by selection of a subset of markers for inclusion in a microarray based genotyping platform. These approaches are expensive, limit genotypes to known markers, can have considerable ascertainment biases, and are not easily amenable to high throughput. We have developed a technically simple, highly multiplexed, high throughput and low cost platform for simultaneous marker discovery and genotyping by sequencing (GBS). Our method can be used in population studies, germplasm characterization, breeding, and trait mapping in diverse organisms. The key features of our Illumina compatible method are (1) reduced genome representation through restriction enzymes (REs), (2) generation of sticky ends to permit the use of lower quality DNA, (3) an inexpensive barcoding system that reduces sample handling and allows single tube digestion and adapter ligation, and (4) barcode length modulation so that sequence quality is not compromised by reading through RE cut-sites. We have processed tens of thousands of samples. In order to do this, we have developed a sample tracking system and integrated robotics. We are developing an open source bioinformatics platform for processing GBS data. This workshop focused on our experience in developing GBS into a high throughput service as well as current research into applying GBS technology to the transcriptome.
More information about GBS can be found on the Institute for Genomic Diversity website. Registration for this satellite educational workshop was limited to attendees of the NERLSCD 2011 meeting. Registration was free but needed to be done separately from registration for the NERLSCD meeting.
This workshop was sponsored with generous support from Illumina and from Wyzer Biosciences.
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New York Core Administration Network (NY-CAN) Meeting
Organizers: Sheenah Mische, New York University, and George Grills, Cornell University
1:00 - 4:00 pm
Wednesday, November 9th, 2011
Weill Hall, Room 321
Cornell University
Ithaca, New York 14853
The NY-Core Administration Network (NY-CAN) is a regional meeting of centralized core administrators from institutions located in NY State. The NY-CAN is a regional spin-off meeting of the ABRF Core Administrators Network, which has a broader national and international scope. The NY-CAN meeting is held on a quarterly basis and is hosted on a rotating basis at different institutions. The meeting format is an informal roundtable discussion by all the participating core administrators. Topics of discussion include a wide variety of regional networking and centralized core administration issues, including the experience of core administrators at formally centralizing core management, instrument acquisition and infrastructure improvement strategies, core involvement in educational outreach activities, external review of cores, how to assure acknowledgement of cores and core staff in publications and grant proposals, how to track the publications and grants supported and enabled by cores, and in light of recent hurricanes in the region, discussion on core facility emergency response plans.
All centralized core administrators attending the NERLSCD meeting were encouraged to attend this satellite event, including attendees from institutions located in NY State and from other states in the region. Registration was free but needed to be done separately from registration for the NERLSCD meeting.
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Tours of core facilities were held Wednesday, Nov. 9, 2011, 4:00-5:30 pm, on the Cornell University campus in Ithaca, NY, right before the NERLSCD 2011 meeting opening reception. These tours were for registered attendees of the NERLSCD 2011 meeting. Registration for the tours was free but needed to be done separately from registration for the NERLSCD meeting.
Tour 1: Cornell University Life Sciences Core Laboratories Center (CLC)
Organizers: George Grills, Peter Schweitzer, Sheng Zhang, Rebecca Williams and Mark Riccio, Cornell University
The CLC provides an array of genomics, proteomics, imaging and informatics shared research resources and services to the university community and to outside investigators. The core center includes fee‐for‐service research, technology testing and development, and educational components. The mission of the CLC is to promote research in the life sciences with advanced technologies in a shared resource environment. The CLC is part of a New York State designated Center for Advanced Technology in Life Science Enterprise. The core center provides coordinated multidisciplinary support for research projects. The CLC facilities include the Genomics Facility, Epigenomics Facility, Proteomics and Mass Spectrometry Facility, Imaging Facility, Bioinformatics Facility / Computational Biology Service Unit (CBSU), Bio-Information Technology Facility (Bio-IT), and Advanced Technology Assessment. The tour focused on the CLC genomics, proteomics, and imaging facilities.
Tour 2: Cornell Center for Materials Research (CCMR)
Organizers: John Grazul and Mick Thomas, Cornell University
The CCMR is a member of the NSF Materials Research Science and Engineering Centers (MRSEC) program. The CCMR facilities comprise an integrated system for materials synthesis and preparation, analysis, testing and characterization, together with an advanced research computing capability. They are used by researchers campus-wide, from other universities, and from government and industrial laboratories. Student users are trained in the use of these sophisticated instruments. The CCMR facilities include the Integrated Advanced Microscopy Facilities, Hudson Mesoscale Processing Facility, Polymer Characterization Facility, Materials Facilities, X-ray Diffraction Facility, and Research Computing Facility. The tour of the CNF focused on the Integrated Advanced Microscopy Facilities, which includes electron microscopy and optical microscopy resources and services.
Tour 3: Cornell NanoScale Science & Technology Facility (CNF)
Organizers: Beth Rhoades and Melanie-Claire Mallison, Cornell University
The Cornell NanoScale Science & Technology Facility, also called the Cornell NanoScale Facility (CNF), is a national user facility. Research at CNF encompasses physical sciences, engineering, and life sciences, and has a strong inter-disciplinary emphasis. Over 700 users per year (50% of who come from outside Cornell) use the fabrication, synthesis, computation, characterization, and integration resources of CNF to build structures, devices, and systems from atomic to complex length-scales.
Tour 4: Cornell Nutrient Analysis Laboratory (CNAL)
Organizer: Michael Rutzke, Cornell University
CNAL provides a wide-range of analyses for a wide diversity of environmental and biological samples using state-of-the-art analytical equipment and techniques. CNAL provides analytical services to researchers, extension educators, state and federal agencies, the food and beverage industry, biotechnology firms, aquaculture companies, crop consultants, farmers, and home gardeners.
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A Taste of Ithaca: Dinner Groups
Attendees of the NERLSCD meeting were encouraged to join Dinner Groups that met on the evening of Thursday, Nov. 10, 2011. This was an opportunity to experience some of the finest restaurants in downtown Ithaca while informally networking with fellow meeting attendees. Dinner Group participants met in the main lobby of the Statler Hotel on Nov. 10th at 7:00 pm for group transportation to the central downtown location of the restaurants, and returned to the hotel at 9:30 pm. This was an optional satellite event and the cost of dinner on Thursday night was not included in the meeting registration fee. Dinner Group included the following outstanding restaurants in Ithaca:
Moosewood Restaurant
An acclaimed driving force in the world of creative vegetarian cooking, Moosewood has a best-selling line of cookbooks and was named one of the most influential restaurants of the 20th Century by Bon Appetit magazine.
Madeline's Restaurant
An extraordinary eating experience for anyone who looks for nontraditional preparation of traditional foods. The cuisine is Euro-Asian, or Pacific Rim, and aims to use the best of Western and Eastern traditions. The deserts are exceptional. Madeline's is listed under “The Best of the Best” in Getaways for Gourmets in the Northeast.
Simeon's On the Commons
Located in an historic building, Simeon’s is an upscale American bistro that provides delectable food and an incredible variety of wines, spirits and beverages. Their cuisine is inspired by the seasonal bounty of the Fingerlakes region.
Ithaca Ale House
Along with a menu of seasonally delicious American fare, the Ale House has an extensive, ever changing 20 tap craft beer selection with brews from all over the country.